Team I Comparative Genomics Group: Difference between revisions
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==== Team members: Heather Patrick, Lawrence McKinney, Laura Mora, Manasa Vegesna, Kenji Gerhardt, Hira Anis ==== | ==== Team members: Heather Patrick, Lawrence McKinney, Laura Mora, Manasa Vegesna, Kenji Gerhardt, Hira Anis ==== | ||
=='''Introduction and Objectives'''== | |||
Comparative genomics is a field in biomedical research in which the genomic features of different organisms are compared. In short, it involves the comparison of one genome to another. This type of comparative analysis can be utilized to discover what lies hidden within the sequences of genomes by comparing sequencing information. Comparative genomics has utilities in gene prediction, regulatory element prediction, phylogenomics, pharmacogenomics, and more. For the purposes of our analysis, we will employ comparative genomics tools to compare bacterial genomes generated from next-generation sequence data generate knowledge that will help us identify and characterize a bacterial outbreak strain of Escherichia coli (''E. coli'') and propose treatment and outbreak identification and containment to public health professional. | |||
Our Data: | |||
#50 isolates of Escherichia coli from an outbreak of foodborne illnesses. The genomes have been assembled and fully annotated. | |||
#Epidemiological data consisting of: times, locations (states), and ingested foods of each case. | |||
==== Stages of analysis and interpretation of data ==== | |||
#[http://compgenomics2020.biosci.gatech.edu/Team_I_Genome_Assembly_Group genome assembly] | |||
#[https://compgenomics2020.biosci.gatech.edu/index.php?title=Team_I_Gene_Prediction_Group&action=edit&redlink=1 gene prediction] | |||
#[http://compgenomics2020.biosci.gatech.edu/index.php?title=Team_I_Functional_Annotation_Group&action=edit&redlink=1 functional annotation] | |||
#[http://compgenomics2020.biosci.gatech.edu/index.php?title=Team_I_Comparative_Genomics_Group&action=edit&redlink=1 comparative genomics] | |||
#[http://compgenomics2020.biosci.gatech.edu/index.php?title=Team_I_Webserver_Group&action=edit&redlink=1 production of a predictive webserver] |
Revision as of 17:17, 12 April 2020
Team 1 Comparative Genomics
Team members: Heather Patrick, Lawrence McKinney, Laura Mora, Manasa Vegesna, Kenji Gerhardt, Hira Anis
Introduction and Objectives
Comparative genomics is a field in biomedical research in which the genomic features of different organisms are compared. In short, it involves the comparison of one genome to another. This type of comparative analysis can be utilized to discover what lies hidden within the sequences of genomes by comparing sequencing information. Comparative genomics has utilities in gene prediction, regulatory element prediction, phylogenomics, pharmacogenomics, and more. For the purposes of our analysis, we will employ comparative genomics tools to compare bacterial genomes generated from next-generation sequence data generate knowledge that will help us identify and characterize a bacterial outbreak strain of Escherichia coli (E. coli) and propose treatment and outbreak identification and containment to public health professional.
Our Data:
- 50 isolates of Escherichia coli from an outbreak of foodborne illnesses. The genomes have been assembled and fully annotated.
- Epidemiological data consisting of: times, locations (states), and ingested foods of each case.