Team II Gene Prediction Group: Difference between revisions

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''Our Objective:'' From assembled genomes, predict genes or features using different prediction methods and evaluate selected tools on their accuracy and performance
''Our Objective:'' From assembled genomes, predict genes or features using different prediction methods and evaluate selected tools on their accuracy and performance
===='''What is Gene Prediction?'''====  
===='''What is Gene Prediction?'''====
Identification of the regions of genomic DNA that encode genes, which are fragments of DNA that encodes a functional molecule:
* Protein-coding genes​
* RNA genes​
* May also include other functional elements (i.e. regulatory regions)


===='''Prokaryotic Genome'''====
===='''Prokaryotic Genome'''====

Revision as of 14:26, 23 February 2020

Team 2: Gene Prediction

Team Members: Danielle Temples, Kara Lee​, Paarth Parekh, Shuting Lin

Introduction

Our Project

Purpose: Investigate an unknown outbreak pathogen using raw genome sequence data from the Centers for Disease Control and Prevention (CDC) foodborne illness surveillance outbreak investigations​

Overall Objective: Identify and characterize the pathogenic organism, make recommendations for the outbreak control, and build a public webserver that automates the computational steps​

Our Objective: From assembled genomes, predict genes or features using different prediction methods and evaluate selected tools on their accuracy and performance

What is Gene Prediction?

Identification of the regions of genomic DNA that encode genes, which are fragments of DNA that encodes a functional molecule:

  • Protein-coding genes​
  • RNA genes​
  • May also include other functional elements (i.e. regulatory regions)

Prokaryotic Genome

Homology Methods

Ab Initio Methods

Tool Evaluation

Non-Coding RNA Methods

Final Pipeline

References