Team II Comparative Genomics Group: Difference between revisions
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== '''Team 2: Comparative Genomics''' == | == '''Team 2: Comparative Genomics''' == | ||
'''Team Members:''' Kara Keun Lee, Courtney Astore, Kristine Lacek, Ujani Hazra, Jayson Chao | '''Team Members:''' Kara Keun Lee, Courtney Astore, Kristine Lacek, Ujani Hazra, Jayson Chao | ||
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== '''Introduction'''== | == '''Introduction'''== | ||
===='''What is Comparative Genomics?'''==== | ===='''What is Comparative Genomics?'''==== | ||
== '''Objectives''' == | |||
* Identify kinds of strains (outbreak vs. sporadic) | |||
*Construct phylogeny demonstrating which isolates are related and which differ | |||
*Determine source of outbreak | |||
*Map virulence and antibiotic resistence features of outbreak isolates | |||
*Compile recommendations for outbreak response and treatment | |||
== '''Overview of Techniques''' == | |||
When performing phylogenomics, there are many options by which one can classify similarities and differences across the genome. Our approach utilizes tools from three different techniques. | |||
=== ''' Hierarical Clustering ''' === | |||
=== ''' MLST ''' === | |||
=== ''' SNP-based ''' === | |||
Revision as of 12:47, 2 March 2020
Team 2: Comparative Genomics
Team Members: Kara Keun Lee, Courtney Astore, Kristine Lacek, Ujani Hazra, Jayson Chao
Introduction
What is Comparative Genomics?
Objectives
- Identify kinds of strains (outbreak vs. sporadic)
- Construct phylogeny demonstrating which isolates are related and which differ
- Determine source of outbreak
- Map virulence and antibiotic resistence features of outbreak isolates
- Compile recommendations for outbreak response and treatment
Overview of Techniques
When performing phylogenomics, there are many options by which one can classify similarities and differences across the genome. Our approach utilizes tools from three different techniques.